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KMID : 0191120180330470296
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Journal of Korean Medical Science
2018 Volume.33 No. 47 p.296 ~ p.296
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Pregnancy Rates and Outcomes of HIV-Infected Women in Korea
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Choi Heun
Kim Moo-Hyun
Lee Se-Ju
Kim Eun-Jin
Lee Woon-Ji
Jeong Woo-Yong
Jung In-Young
Ahn Jin-Young
Jeong Su-Jin
Ku Nam-Su
Baek Ji-Hyeon
Choi Young-Hwa
Kim Hyo-Youl
Kim June-Myung
Choi Jun-Yong
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Abstract
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Background: Antepartum, intrapartum, and postpartum preventive measures with antiretroviral drugs, appropriate delivery methods, and discouraging breastfeeding significantly decrease the risk of mother-to-child transmission of human immunodeficiency virus (HIV) infection. Herein, we investigated the pregnancy outcomes in HIV-infected Korean women.
Methods: We retrospectively reviewed medical records of childbearing-age HIV-infected women between January 2005 and June 2017 at four tertiary care hospitals in Korea.
Results: Among a total of 95 HIV infected women of child-bearing age with 587.61 years of follow-up duration, 15 HIV-infected women experienced 21 pregnancies and delivered 16 infants. The pregnancy rate was 3.57 per 100 patient-years. Among the 21 pregnancies, five ended with an induced abortion, and 16 with childbirth including two preterm deliveries at 24 and 35 weeks of gestation, respectively. The two preterm infants had low birth weight and one of them died 10 days after delivery due to respiratory failure. Among the 14 full-term infants, one infant was small for gestational age. There were no HIV-infected infants.
Conclusion: The pregnancy rate of HIV-infected women in Korea is lower than that of the general population. Although several adverse pregnancy outcomes were observed, mother-to-child transmission of HIV infection was successfully prevented with effective preventive measures.
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KEYWORD
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HIV, Mother-to-Child Transmission, Pregnancy Outcomes, Pregnancy Rate
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